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KMID : 0356920200730020163
Korean Journal of Anesthesiology
2020 Volume.73 No. 2 p.163 ~ p.168
Ultrasound-guided percutaneous intercostal cryoanalgesia for multiple weeks of analgesia following mastectomy: a case series
Gabriel Rodney A.

Finneran John J.
Swisher Matthew W.
Said Engy T.
Sztain Jacklynn F.
Khatibi Bahareh
Wallace Anne M.
Hosseini Ava
Trescot Andrea M.
Ilfeld Brian M.
Abstract
Background: Acute post-mastectomy pain is frequently challenging to adequately treat with local anesthetic-based regional anesthesia techniques due to its relatively long duration measured in multiple weeks.

Case: We report three cases in which preoperative ultrasound-guided percutaneous intercostal nerve cryoneurolysis was performed to treat pain following mastectomy. Across all postoperative days and all three patients, the mean pain score on the numeric rating scale was 0 for each day. Similarly, no patient required any supplemental opioid analgesics during the entire postoperative period; and, no patient reported insomnia or awakenings due to pain at any time point. This was a significant improvement over historic cohorts.

Conclusions: Ultrasound-guided percutaneous cryoanalgesia is a potential novel analgesic modality for acute pain management which has a duration that better-matches mastectomy than other currently-described techniques. Appropriately powered randomized, controlled clinical trials are required to demonstrate and quantify both potential benefits and risks.
KEYWORD
Acute pain, Cryoanalgesia, Cryoneurolysis, Mastectomy, Regional anesthesia
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